In vivo live imaging of RNA polymerase II transcription factories in primary cells

Transcription steps are marked by different modifications of the C-terminal domain of RNA polymerase II (RNAPII). Phosphorylation of Ser5 and Ser7 by cyclin-dependent kinase 7 (CDK7) as part of TFIIH marks initiation, whereas phosphorylation of Ser2 by CDK9 marks elongation. These processes are thou...

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Detalhes bibliográficos
Main Authors: Ghamari, Alireza, van de Corput, Mariëtte P.C., Thongjuea, Supat, van Cappellen, Wiggert A., van IJcken, Wilfred, van Haren, Jeffrey, Soler, Eric, Eick, Dirk, Lenhard, Boris, Grosveld, Frank G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639417/
https://ncbi.nlm.nih.gov/pubmed/23592796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.216200.113
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