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In Vitro Drug Response and Efflux Transporters Associated with Drug Resistance in Pediatric High Grade Glioma and Diffuse Intrinsic Pontine Glioma

Pediatric high-grade gliomas (pHGG), including diffuse intrinsic pontine gliomas (DIPG), are the leading cause of cancer-related death in children. While it is clear that surgery (if possible), and radiotherapy are beneficial for treatment, the role of chemotherapy for these tumors is still unclear....

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Detalhes bibliográficos
Main Authors: Veringa, Susanna J. E., Biesmans, Dennis, van Vuurden, Dannis G., Jansen, Marc H. A., Wedekind, Laurine E., Horsman, Ilona, Wesseling, Pieter, Vandertop, William Peter, Noske, David P., Kaspers, GertJan J. L., Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639279/
https://ncbi.nlm.nih.gov/pubmed/23637844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061512
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