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Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation: an update

Intravenous vernakalant has recently been approved in Europe as an atrial-selective antiarrhythmic drug for the conversion of recent-onset atrial fibrillation (AF). It inhibits atrial-selective K(+) currents (I(K,ACh) and I(Kur)) and causes rate-dependent atrial-predominant Na(+) channel block, with...

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Bibliographic Details
Main Authors: Tsuji, Yukiomi, Dobrev, Dobromir
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639220/
https://ncbi.nlm.nih.gov/pubmed/23637539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/VHRM.S43720
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