A three-gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer

OBJECTIVE: Personalized chemotherapy based on molecular biomarkers can maximize anticancer efficiency. We aim to investigate predictive biomarkers capable of predicting response to irinotecan-based treatment in gastric cancer. METHODS: We examined gene expression of APTX, BRCA1, ERCC1, ISG15, Topo1...

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Main Authors: Shen, Jie, Wei, Jia, Wang, Hao, Yue, Guofeng, Yu, Lixia, Yang, Yang, Xie, Li, Zou, Zhengyun, Qian, Xiaoping, Ding, Yitao, Guan, Wenxian, Liu, Baorui
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639168/
https://ncbi.nlm.nih.gov/pubmed/23517622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-73
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