VEGF mediates commissural axon chemoattraction through its receptor Flk1

Growing axons are guided to their targets by attractive and repulsive cues. In the developing spinal cord, Netrin-1 and Shh guide commissural axons towards the midline. However, the combined inhibition of their activity in commissural axon turning assays does not completely abrogate turning towards...

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Hauptverfasser: de Almodovar, Carmen Ruiz, Fabre, Pierre J., Knevels, Ellen, Coulon, Cathy, Segura, Inmaculada, Haddick, Patrick C.G., Aerts, Liesbeth, Delattin, Nicolas, Strasser, Geraldine, Oh, Won-Jong, Lange, Christian, Vinckier, Stefan, Haigh, Jody, Fouquet, Coralie, Henderson, Christopher, Gu, Chengua, Alitalo, Kari, Castellani, Valerie, Tessier-Lavigne, Marc, Chedotal, Alain, Charron, Frederic, Carmeliet, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638787/
https://ncbi.nlm.nih.gov/pubmed/21658588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.04.014
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