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Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis
The cyclic nucleotides cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) regulate the activity of protein kinase A (PKA) and protein kinase G (PKG), respectively. This process helps maintain circulating platelets in a resting state. Here we studied the role of cAMP and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638753/ https://ncbi.nlm.nih.gov/pubmed/22981933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2012.09.001 |
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