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The failure of animal models of neuroprotection in acute ischemic stroke to translate to clinical efficacy
Summary The discrepancy in results regarding neuroprotective agents in animal experiments compared to clinical trials is a major problem. While many neuroprotective agents have been proven effective in a variety of animal ischemic stroke models, none have been shown to work in phase III clinical tri...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
International Scientific Literature, Inc.
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638705/ https://ncbi.nlm.nih.gov/pubmed/23353570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSMBR.883750 |
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