Phase I Study of Ofatumumab, a Human Anti-CD20 Antibody, in Japanese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

OBJECTIVES: Ofatumumab is a human IgG1κ monoclonal antibody that targets a membrane proximal epitope encompassing the small and large loops of CD20. This Phase I study evaluated the safety, tolerability, efficacy and pharmacokinetics of ofatumumab monotherapy in Japanese patients with relapsed/refra...

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Detalhes bibliográficos
Main Authors: Ogura, Michinori, Hatake, Kiyohiko, Tobinai, Kensei, Uchida, Toshiki, Suzuki, Tatsuya, Terui, Yasuhito, Yokoyama, Masahiro, Maruyama, Dai, Mori, Masakazu, Jewell, Roxanne C., Katsura, Koichi, Hotta, Tomomitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638632/
https://ncbi.nlm.nih.gov/pubmed/23456745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jjco/hyt022
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