Cyclohexylmethyl Flavonoids Suppress Propagation of Breast Cancer Stem Cells via Downregulation of NANOG

Breast cancer stem cells (CSCs) are highly tumorigenic and possess the capacity to self-renew. Recent studies indicated that pluripotent gene NANOG involves in regulating self-renewal of breast CSCs, and expression of NANOG is correlated with aggressiveness of poorly differentiated breast cancer. We...

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Autors principals: Liao, Wen-Ying, Liaw, Chih-Chuang, Huang, Yuan-Chao, Han, Hsin-Ying, Hsu, Hung-Wei, Hwang, Shiaw-Min, Kuo, Sheng-Chu, Shen, Chia-Ning
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638599/
https://ncbi.nlm.nih.gov/pubmed/23662114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/170261
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