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An integrative, translational approach to understanding rare and orphan genetically based diseases

PhenomeNet is an approach for integrating phenotypes across species and identifying candidate genes for genetic diseases based on the similarity between a disease and animal model phenotypes. In contrast to ‘guilt-by-association’ approaches, PhenomeNet relies exclusively on the comparison of phenoty...

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Autori principali: Hoehndorf, Robert, Schofield, Paul N., Gkoutos, Georgios V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638468/
https://ncbi.nlm.nih.gov/pubmed/23853703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2012.0055
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