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l-dopa-induced dopamine synthesis and oxidative stress in serotonergic cells

l-dopa is a precursor for dopamine synthesis and a mainstay treatment for Parkinson's disease. However, l-dopa therapy is not without side effects that may be attributed to non-dopaminergic mechanisms. Synthesized dopamine can be neurotoxic through its enzymatic degradation by monoamine oxidase...

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Detalhes bibliográficos
Main Authors: Stansley, Branden J., Yamamoto, Bryan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638241/
https://ncbi.nlm.nih.gov/pubmed/23196068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.11.010
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