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Synergistic Induction of miR-126 by Hypoxia and HDAC Inhibitors in Cardiac Myocytes

HDAC inhibitors are under clinical development for the treatment of hypertrophic cardiomyopathy and heart failure although the mechanisms of protection are incompletely understood. Micro-RNA 126, an endothelium-specific miR has been assigned essential developmental roles in the heart by activating s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shi, Huaping, Chen, Lei, Wang, Huilan, Zhu, Shaokang, Dong, Chunming, Webster, Keith A., Wei, Jianqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638006/
https://ncbi.nlm.nih.gov/pubmed/23201405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.061
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