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Modulating Cocaine Vaccine Potency Through Hapten Fluorination

Cocaine addiction is a long-lasting relapsing illness characterized by cycles of abuse, abstinence and reinstatement, and antibody-based therapies could be a powerful therapeutic approach. Herein, we explored the possibility of using halogenated cocaine haptens to enhance the immunological propertie...

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Detalhes bibliográficos
Main Authors: Cai, Xiaoqing, Tsuchikama, Kyoji, Janda, Kim D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637684/
https://ncbi.nlm.nih.gov/pubmed/23398531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja400356g
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