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Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression Without Cell Division

We sought to evaluate the relationship between cell division and protein expression when using commercial poly(ethylenimine) (PEI)-based polyplexes. The membrane dye PKH26 was used to assess cell division, and cyan fluorescent protein (CFP) was used to monitor protein expression. When analyzed at th...

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Hlavní autoři: Matz, Rebecca L., Erickson, Blake, Vaidyanathan, Sriram, Kukowska-Latallo, Jolanta F., Baker, James R., Orr, Bradford G., Banaszak Holl, Mark M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637663/
https://ncbi.nlm.nih.gov/pubmed/23458572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300470d
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