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Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression Without Cell Division

We sought to evaluate the relationship between cell division and protein expression when using commercial poly(ethylenimine) (PEI)-based polyplexes. The membrane dye PKH26 was used to assess cell division, and cyan fluorescent protein (CFP) was used to monitor protein expression. When analyzed at th...

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Detalhes bibliográficos
Main Authors: Matz, Rebecca L., Erickson, Blake, Vaidyanathan, Sriram, Kukowska-Latallo, Jolanta F., Baker, James R., Orr, Bradford G., Banaszak Holl, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637663/
https://ncbi.nlm.nih.gov/pubmed/23458572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300470d
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