RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation

BACKGROUND: Recent work has shown that the chaperone resistant to inhibitors of acetylcholinesterase (RIC-3) is critical for the folding, maturation and functional expression of a variety of neuronal nicotinic acetylcholine receptors. α7 nicotinic receptors can only assemble and functionally express...

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Autores principales: Dau, Alejandro, Komal, Pragya, Truong, Mimi, Morris, Geoff, Evans, Gareth, Nashmi, Raad
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637639/
https://ncbi.nlm.nih.gov/pubmed/23586521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-47
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