Safety and efficacy of duloxetine treatment in older and younger patients with osteoarthritis knee pain: a post hoc, subgroup analysis of two randomized, placebo-controlled trials

BACKGROUND: Osteoarthritis (OA) knee pain is common in older patients and contributes to decreased quality of life. Older patients are generally at higher risk of adverse drug reactions due to age-related changes in physiology that affect drug disposition, metabolism, and response. These analyses ex...

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Hlavní autoři: Micca, Joseph L, Ruff, Dustin, Ahl, Jonna, Wohlreich, Madelaine M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637531/
https://ncbi.nlm.nih.gov/pubmed/23590727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-137
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