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Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina

BACKGROUND: Gab1 (Grb2-associated binder 1) is a key coordinator that belongs to the insulin receptor substrate-1 like family of adaptor molecules and is tyrosine phosphorylated in response to various growth factors, cytokines, and numerous other molecules. Tyrosine phosphorylated Gab1 is able to re...

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Autors principals: Rajala, Ammaji, Dilly, Ashok K, Rajala, Raju VS
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637500/
https://ncbi.nlm.nih.gov/pubmed/23521888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-20
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