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Embryonic Stem Cells Are Redirected to Non-Tumorigenic Epithelial Cell Fate by Interaction with the Mammary Microenvironment

Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1∶5 and 1∶50 in phosphate buffered saline and immediately inocula...

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Bibliografiset tiedot
Päätekijät: Boulanger, Corinne A., Bruno, Robert D., Mack, David L., Gonzales, Monica, Castro, Nadia P., Salomon, David S., Smith, Gilbert H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637449/
https://ncbi.nlm.nih.gov/pubmed/23637952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062019
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