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Transfection of a human gene that corrects the Lec1 glycosylation defect: evidence for transfer of the structural gene for N-acetylglucosaminyltransferase I.

Chinese hamster ovary (CHO) glycosylation mutants provide an approach to cloning mammalian glycosyltransferases by transfection and gene rescue. In this paper, complementation of the lec1 CHO mutation by human DNA is described. Lec1 transfectants expressed human N-acetylglucosaminyltransferase I (Gl...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Kumar, R, Stanley, P
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5713-5717.1989
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