Single-cell microarray enables high-throughput evaluation of DNA double-strand breaks and DNA repair inhibitors

A key modality of non-surgical cancer management is DNA damaging therapy that causes DNA double-strand breaks that are preferentially toxic to rapidly dividing cancer cells. Double-strand break repair capacity is recognized as an important mechanism in drug resistance and is therefore a potential ta...

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Autores principales: Weingeist, David M., Ge, Jing, Wood, David K., Mutamba, James T., Huang, Qiuying, Rowland, Elizabeth A., Yaffe, Michael B., Floyd, Scott, Engelward, Bevin P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637349/
https://ncbi.nlm.nih.gov/pubmed/23422001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23880
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