Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein.

The bovine papillomavirus (BPV) type 1 E5 gene encodes a 44-amino-acid protein that can stably transform cultured rodent cells when expressed in the absence of all other viral genes. We have previously constructed a BPV-simian virus 40 recombinant virus (Pava-1) which efficiently expresses the BPV t...

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Main Authors: Settleman, J, Fazeli, A, Malicki, J, Horwitz, B H, DiMaio, D
格式: Artigo
語言:Inglês
出版: 1989
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC363726/
https://ncbi.nlm.nih.gov/pubmed/2555701
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