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Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein.

The bovine papillomavirus (BPV) type 1 E5 gene encodes a 44-amino-acid protein that can stably transform cultured rodent cells when expressed in the absence of all other viral genes. We have previously constructed a BPV-simian virus 40 recombinant virus (Pava-1) which efficiently expresses the BPV t...

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Publicat a:Mol Cell Biol
Autors principals: Settleman, J, Fazeli, A, Malicki, J, Horwitz, B H, DiMaio, D
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5563-5572.1989
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