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Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein.
The bovine papillomavirus (BPV) type 1 E5 gene encodes a 44-amino-acid protein that can stably transform cultured rodent cells when expressed in the absence of all other viral genes. We have previously constructed a BPV-simian virus 40 recombinant virus (Pava-1) which efficiently expresses the BPV t...
Kaydedildi:
Asıl Yazarlar: | , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
1989
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC363726/ https://ncbi.nlm.nih.gov/pubmed/2555701 |
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