Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells

This study examined whether combining paclitaxel (taxol) with a novel epigenetic agent phenethyl isothiocyanate (PEITC) will yield a synergistic effect on inhibiting breast cancer cells. Two drug-resistant breast cancer cell lines, MCF7 and MDA-MB-231, were treated with PEITC and taxol. Cell growth,...

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Autores principales: Liu, Katherine, Cang, Shundong, Ma, Yuehua, Chiao, Jen Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637186/
https://ncbi.nlm.nih.gov/pubmed/23388416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-10
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