Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.

Glucocorticoids rapidly and specifically inhibit transcription of the pro-opiomelanocortin (POMC) gene in the anterior pituitary, thus offering a model for studying negative control of transcription in mammals. We have defined an element within the rat POMC gene 5'-flanking region that is required f...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Drouin, J, Trifiro, M A, Plante, R K, Nemer, M, Eriksson, P, Wrange, O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2586521/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5305-5314.1989
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