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Mediator Recruitment to Heat Shock Genes Requires Dual Hsf1 Activation Domains and Mediator Tail Subunits Med15 and Med16

The evolutionarily conserved Mediator complex is central to the regulation of gene transcription in eukaryotes because it serves as a physical and functional interface between upstream regulators and the Pol II transcriptional machinery. Nonetheless, its role appears to be context-dependent, and the...

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Detalhes bibliográficos
Main Authors: Kim, Sunyoung, Gross, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636903/
https://ncbi.nlm.nih.gov/pubmed/23447536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.449553
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