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Novelty-induced conditioned place preference, sucrose preference, and elevated plus maze behavior in adult rats after repeated exposure to methylphenidate during the preweanling period

Early treatment with methylphenidate has a persistent effect on the affective (i.e., anxiety- and depressive-like) behaviors of adult rats and mice. Interestingly, age at methylphenidate exposure appears to be a critical determinant influencing the expression of affective behaviors. In the present s...

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Detalhes bibliográficos
Main Authors: Crawford, Cynthia A., Der-Ghazarian, Taleen, Britt, Cynthia E., Varela, Fausto A., Kozanian, Olga O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636810/
https://ncbi.nlm.nih.gov/pubmed/23466690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.02.031
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