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Protein Carbamylation Predicts Mortality in ESRD

Traditional risk factors fail to explain the increased risk for cardiovascular morbidity and mortality in ESRD. Cyanate, a reactive electrophilic species in equilibrium with urea, posttranslationally modifies proteins through a process called carbamylation, which promotes atherosclerosis. The plasma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Koeth, Robert A., Kalantar-Zadeh, Kamyar, Wang, Zeneng, Fu, Xiaoming, Tang, W.H. Wilson, Hazen, Stanley L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636787/
https://ncbi.nlm.nih.gov/pubmed/23431074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030254
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