Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase

PHF2 is a JmjC family histone demethylase that removes the methyl group from H3K9me2 and works as a coactivator for several metabolism-related transcription factors. In this study, we examined the in vivo role of PHF2 in mice. We generated Phf2 floxed mice, systemic Phf2 null mice by crossing Phf2 f...

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Bibliographic Details
Main Authors: Okuno, Yosuke, Ohtake, Fumiaki, Igarashi, Katsuhide, Kanno, Jun, Matsumoto, Takahiro, Takada, Ichiro, Kato, Shigeaki, Imai, Yuuki
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636657/
https://ncbi.nlm.nih.gov/pubmed/23274892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0628
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