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Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression.

The single-copy gene encoding the alpha subunit of glycoprotein hormones is expressed in the pituitaries of all mammals and in the placentas of only primates and horses. We have systematically analyzed the promoter-regulatory elements of the human and bovine alpha-subunit genes to elucidate the mole...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Bokar, J A, Keri, R A, Farmerie, T A, Fenstermaker, R A, Andersen, B, Hamernik, D L, Yun, J, Wagner, T, Nilson, J H
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1989
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2481230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.11.5113-5122.1989
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