Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis

Type II endometrial cancer (EMCA) represents only 10% of all EMCAs, but accounts for 40% of EMCA-related mortality. Previous studies of human tumors have shown an association between Type II tumors and damaged telomeres. We hypothesized that the lack of murine Type II EMCA models is due to the extre...

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Bibliografiske detaljer
Main Authors: Akbay, E A, Peña, C G, Ruder, D, Michel, J A, Nakada, Y, Pathak, S, Multani, A S, Chang, S, Castrillon, D H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636499/
https://ncbi.nlm.nih.gov/pubmed/22689059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.232
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