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MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart

MicroRNAs (miRs) are small non- coding RNA molecules controlling a plethora of biological processes such as development, cellular survival and senescence. We here determined miRs differentially regulated during cardiac postnatal development and aging. Cardiac function, morphology and miR expression...

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Detalhes bibliográficos
Main Authors: Jazbutyte, Virginija, Fiedler, Jan, Kneitz, Susanne, Galuppo, Paolo, Just, Annette, Holzmann, Angelika, Bauersachs, Johann, Thum, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636396/
https://ncbi.nlm.nih.gov/pubmed/22538858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9407-9
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