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Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer’s disease

With aging and Alzheimer’s disease (AD), there is an increased sensitivity to stress along with declines in the memory-associated neurotrophin brain-derived neurotrophic factor in AD. We have replicated this aging phenotype in cultured neurons from aged mice despite being grown in the same environme...

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Detalhes bibliográficos
Main Authors: Walker, Michael P., LaFerla, Frank M., Oddo, Salvador S., Brewer, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636384/
https://ncbi.nlm.nih.gov/pubmed/22237558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9375-5
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