Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

BACKGROUND: Macrophage death in advanced lesion has been confirmed to play an important role in plaque instability. However, the mechanism underlying lesion macrophage death still remains largely unknown. METHODS AND RESULTS: Immunohistochemistry showed that caspase-1 activated in advanced lesion an...

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Detalhes bibliográficos
Main Authors: Lin, Jing, Shou, Xiling, Mao, Xiaobo, Dong, Jiangchuan, Mohabeer, Nilesh, Kushwaha, Kishan kumar, Wang, Lei, Su, Yousu, Fang, Hongcheng, Li, Dazhu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636212/
https://ncbi.nlm.nih.gov/pubmed/23637985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062148
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