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Modulating alignment of membrane proteins in liquid-crystalline and oriented gel media by changing the size and charge of phospholipid bicelles

We demonstrate that alignment of a structured peptide or small protein solubilized in mixed phospholipid:detergent micelles or bicelles, when embedded in a compressed gel or liquid crystalline medium, can be altered by either changing the phospholipid aggregate shape, charge, or both together. For t...

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Detalhes bibliográficos
Main Authors: Lorieau, Justin L, Maltsev, Alexander S., Louis, John M, Bax, Ad
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636151/
https://ncbi.nlm.nih.gov/pubmed/23508769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-013-9720-3
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