Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-α

BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is elevated early in injured brain after traumatic brain injury (TBI), in humans and in animals. Etanercept (a TNF-α antagonist with anti-inflammatory effects) attenuates TBI in rats by reducing both microglial and astrocytic activation and increased s...

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Hlavní autoři: Chio, Chung-Ching, Chang, Chin-Hong, Wang, Che-Chuan, Cheong, Chong-Un, Chao, Chien-Ming, Cheng, Bor-Chih, Yang, Chung-Zhing, Chang, Ching-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636122/
https://ncbi.nlm.nih.gov/pubmed/23496862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-33
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