Early Apoptosis of Macrophages Modulated by Injection of Yersinia pestis YopK Promotes Progression of Primary Pneumonic Plague

Yersinia pestis causes pneumonic plague, a disease characterized by inflammation, necrosis and rapid bacterial growth which together cause acute lung congestion and lethality. The bacterial type III secretion system (T3SS) injects 7 effector proteins into host cells and their combined activities are...

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Autors principals: Peters, Kristen N., Dhariwala, Miqdad O., Hughes Hanks, Jennifer M., Brown, Charles R., Anderson, Deborah M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636031/
https://ncbi.nlm.nih.gov/pubmed/23633954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003324
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