Localization of Protein Aggregation in Escherichia coli Is Governed by Diffusion and Nucleoid Macromolecular Crowding Effect

Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium. Because of the potential of E. coli as a model organism, elucidating...

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Bibliographic Details
Main Authors: Coquel, Anne-Sophie, Jacob, Jean-Pascal, Primet, Mael, Demarez, Alice, Dimiccoli, Mariella, Julou, Thomas, Moisan, Lionel, Lindner, Ariel B., Berry, Hugues
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636022/
https://ncbi.nlm.nih.gov/pubmed/23633942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003038
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