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Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing

Intrinsically disordered regions have been associated with various cellular processes and are implicated in several human diseases, but their exact roles remain unclear. We previously defined two classes of conserved disordered regions in budding yeast, referred to as “flexible” and “constrained” co...

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Detalhes bibliográficos
Main Authors: Colak, Recep, Kim, TaeHyung, Michaut, Magali, Sun, Mark, Irimia, Manuel, Bellay, Jeremy, Myers, Chad L., Blencowe, Benjamin J., Kim, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635989/
https://ncbi.nlm.nih.gov/pubmed/23633940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003030
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