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The Chlamydia pneumoniae Invasin Protein Pmp21 Recruits the EGF Receptor for Host Cell Entry

Infection of mammalian cells by the strictly intracellular pathogens Chlamydiae requires adhesion and internalization of the infectious Elementary Bodies (EBs). The components of the latter step were unknown. Here, we identify Chlamydia pneumoniae Pmp21 as an invasin and EGFR as its receptor. Modula...

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Autors principals: Mölleken, Katja, Becker, Elisabeth, Hegemann, Johannes H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635982/
https://ncbi.nlm.nih.gov/pubmed/23633955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003325
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