CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling

NF-κB is a master regulator of inflammation and has been implicated in the pathogenesis of immune disorders and cancer. Its regulation involves a variety of steps, including the controlled degradation of inhibitory IκB proteins. In addition, the inactivation of DNA-bound NF-κB is essential for its r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Starokadomskyy, Petro, Gluck, Nathan, Li, Haiying, Chen, Baozhi, Wallis, Mathew, Maine, Gabriel N., Mao, Xicheng, Zaidi, Iram W., Hein, Marco Y., McDonald, Fiona J., Lenzner, Steffen, Zecha, Agnes, Ropers, Hans-Hilger, Kuss, Andreas W., McGaughran, Julie, Gecz, Jozef, Burstein, Ezra
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635737/
https://ncbi.nlm.nih.gov/pubmed/23563313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66466
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