Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions

Large regions of recurrent genomic loss are common in cancers; however, with a few well-characterized exceptions, how they contribute to tumor pathogenesis remains largely obscure. Here we identified primate-restricted imprinting of a gene cluster on chromosome 20 in the region commonly deleted in c...

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Detalhes bibliográficos
Main Authors: Aziz, Athar, Baxter, E. Joanna, Edwards, Carol, Cheong, Clara Yujing, Ito, Mitsuteru, Bench, Anthony, Kelley, Rebecca, Silber, Yvonne, Beer, Philip A., Chng, Keefe, Renfree, Marilyn B., McEwen, Kirsten, Gray, Dionne, Nangalia, Jyoti, Mufti, Ghulam J., Hellstrom-Lindberg, Eva, Kiladjian, Jean-Jacques, McMullin, Mary Frances, Campbell, Peter J., Ferguson-Smith, Anne C., Green, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635733/
https://ncbi.nlm.nih.gov/pubmed/23543057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66113
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