Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae

Retinal vessel homeostasis ensures normal ocular functions. Consequently, retinal hypovascularization and neovascularization, causing a lack and an excess of vessels, respectively, are hallmarks of human retinal pathology. We provide evidence that EC-specific genetic ablation of either the transcrip...

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Detalhes bibliográficos
Main Authors: Weinl, Christine, Riehle, Heidemarie, Park, Dongjeong, Stritt, Christine, Beck, Susanne, Huber, Gesine, Wolburg, Hartwig, Olson, Eric N., Seeliger, Mathias W., Adams, Ralf H., Nordheim, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635718/
https://ncbi.nlm.nih.gov/pubmed/23563308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64201
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