Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme

BACKGROUND: Glutamine synthetase (GS) is an astrocytic enzyme catalyzing the conversion of glutamate and ammonia to glutamine. Its up-regulation has been related to higher tumor proliferation and poor prognosis in extra-cerebral tumors. We have previously reported a GS deficiency in patients with gl...

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Detalhes bibliográficos
Main Authors: Rosati, Anna, Poliani, Pietro Luigi, Todeschini, Alice, Cominelli, Manuela, Medicina, Daniela, Cenzato, Marco, Simoncini, Edda Lucia, Magrini, Stefano Maria, Buglione, Michela, Grisanti, Salvatore, Padovani, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635515/
https://ncbi.nlm.nih.gov/pubmed/23410662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos338
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