Protein Carbamylation in Chronic Systolic Heart Failure: Relation to Renal Impairment and Adverse Long-Term Outcomes

BACKGROUND: Protein carbamylation, a post-translational modification promoted during uremia and catalyzed by myeloperoxidase (MPO) at sites of inflammation, is linked to altered protein structure, vascular dysfunction, and poor prognosis. We examine the relationship between plasma protein-bound homo...

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Main Authors: Wilson Tang, W. H., Shrestha, Kevin, Wang, Zeneng, Borowski, Allen G., Troughton, Richard W., Klein, Allan L., Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635500/
https://ncbi.nlm.nih.gov/pubmed/23582087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2013.02.001
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