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Molecular targets and mechanisms of radiosensitization using DNA damage response pathways
The cellular reaction to genomic instability includes a network of signal transduction pathways collectively referred to as the DNA damage response (DDR). Activated by a variety of DNA lesions, the DDR orchestrates cell cycle arrest and DNA repair, and initiates apoptosis in instances where damage c...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635474/ https://ncbi.nlm.nih.gov/pubmed/23414472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.12.185 |
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