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Depletion of PtdIns(4,5)P(2) underlies retinal degeneration in Drosophila trp mutants
The prototypical transient receptor potential (TRP) channel is the major light-sensitive, and Ca(2+)-permeable channel in the microvillar photoreceptors of Drosophila. TRP channels are activated following hydrolysis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] by the key effector enzym...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635464/ https://ncbi.nlm.nih.gov/pubmed/23378018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.120592 |
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