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Scale-up and Validation of a MALDI-MS-based Inhibitor Screening Technology

Recently, mass spectrometry (MS)-based readout has been demonstrated to be a highly effective for high throughput screening (HTS) assays. The major advantages compared to the most common fluorescence readout are the paucity of false readouts, reduced reagent costs, and the ability to multiplex assay...

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Main Authors: Kirby, Richard J., Nelson, Sandra L., Seibel, William L., Papoian, Ruben, Greis, Kenneth D., Rathore, Rakesh
Format: Artigo
Jezik:Inglês
Izdano: Association of Biomolecular Resource Facilities 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635425/
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