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Targeted gene modifications have been advanced by the use of engineered nucleases that make a double strand break (DSB) in genomic DNA. When the cell responds to the DSB by either the imperfect repair process of non-homologous end joining (NHEJ) or by homologous recombination (HR) from a donor templ...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association of Biomolecular Resource Facilities
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635368/ |
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