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Requirement of one functional RAS gene and inability of an oncogenic ras variant to mediate the glucose-induced cyclic AMP signal in the yeast Saccharomyces cerevisiae.

Addition of glucose to Saccharomyces cerevisiae cells grown on a nonfermentable carbon source triggers a cyclic AMP (cAMP) signal, which induces a protein phosphorylation cascade. In a yeast strain lacking functional RAS1 and RAS2 genes and containing a bcy mutation to suppress the lethality of RAS...

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Publicat a:Mol Cell Biol
Autors principals: Mbonyi, K, Beullens, M, Detremerie, K, Geerts, L, Thevelein, J M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2850478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3051-3057.1988
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