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The Advantages of Micro-Cal™ Auto-iTC200 for Secondary Screening in a Fragment-based Drug Discovery Campaign

Background: Recent developments in ITC instrumentation, namely MicroCal iTC200 and MicroCal Auto-iTC200 have led to an increase in the throughput and decrease in the protein consumption of the technique. In addition, there have been recent methodological Advancements 1 that have extended the affinit...

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Main Authors: Markova, Natalia, O'Brien, Ronan, Martinsson, Jessica, Halberg, Kenth, Andersson, Martin, Welin, Martin, Arsenault, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Association of Biomolecular Resource Facilities 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635267/
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