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The E1a gene of adenovirus type 2 reduces the metastatic potential of ras-transformed rat embryo cells.

We have previously demonstrated that second-passage rat embryo cells transformed by the ras oncogene alone are both tumorigenic and highly metastatic when injected into nude mice. In contrast, rat embryo cells cotransformed with the ras oncogene and the adenovirus type 2 (Ad2) E1a gene are tumorigen...

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Publicado en:Mol Cell Biol
Principais autores: Pozzatti, R, McCormick, M, Thompson, M A, Khoury, G
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363519/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2970008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.7.2984-2988.1988
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